Modeling the evolution of influenza in human population

Program in Applied and Computational Mathematics, Princeton University, USA

Sergey Kryazhimskiy

Sergey Kryazhimskiy

Influenza is a well known respiratory disease that, perhaps unexpectedly, is one of the most important causes of mortality and morbidity worldwide. RNA viruses such as influenza are characterized by an extremely high mutation rate. This ability allows influenza to evolve its surface proteins so fast that the human immune system cannot keep up – that's why we get sick with flu more than once in our life. In my project I study the peculiarities of the evolution of the Influenza A using mathematical models. I am trying to tie together analytical models, deterministic computer models and stochastic individual-based simulations. In my presentation I will discuss those features that distinguish influenza from other viruses. I will also talk shortly about some preliminary results that I have got so far.

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Last edited: 25 March 2016

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