Great diversity has been found in the phylogenetic, or "genealogical tree", relationship within the species of pathogens. Quite little is known, however, on how these striking differences in tree shapes are related to epidemiological parameters like transmission rate, virulence, and recovery rate, and to the population genetical parameters. In this study, I simulate a host-pathogen system, generate phylogenetic trees from the simulation, and then analyze how their characteristics are related to epidemiological and genetical parameters.
International Institute for Applied Systems Analysis (IIASA)
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